Paternity Testing
نویسنده
چکیده
Paternity testing can be done by older methods including ABO blood group typing, analysis of various other proteins and enzymes, or using human leukocyte antigen (HLA). However, DNA testing became the only formal and exact method for the paternity testing now. For DNA testing of paternity determination, the DNA collection using an easily obtained cheek swab saliva sample. Fast, proprietary and confidential genetic profiling of the child and alleged father with 99.999% probability/accuracy of results. In the common DNA paternity case, the alleged father and child are tested using polymerase chain reaction (PCR), Short tandem repeat (STR) and restriction fragment length polymorphism (RFLP) methodologies. Results for a DNA paternity case are available in an average of 3-4 days from receipt by the most paternity testing laboratory. Cheek swab saliva testing can be done immediately after birth, and typically the child and alleged father are tested. Results exclude or confirm the biological father with an accuracy rate exceeding 99.9%. [The Journal of American Science. 2006;2(4):76-92].
منابع مشابه
Paternity Testing Commission of the International Society of Forensic Genetics: recommendations on genetic investigations in paternity cases.
The International Society for Forensic Genetics (ISFG) has established a Paternity Testing Commission (PTC) with the purpose of formulating international recommendations concerning genetic investigations in paternity testing. The PTC recommends that paternity testing be performed in accordance with the ISO 17025 standards. The ISO 17025 standards are general standards for testing laboratories a...
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DNA paternity testing has recently become more widely available in Japan. The aim of this paper is to examine the issues surrounding (1) the implementing agency, whether the testing is conducted in a commercial direct-to-consumer (DTC) setting or a judicial non-DTC setting, and (2) the implementation conditions and more specifically the legal capacity of the proband (test subject). Literature r...
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We have developed a SNP microarray for paternity testing, which contains 10 SNPs and in addition X and Y chromosome-specific markers. SNPs were selected with an emphasis on their high allele frequency in the Finnish population. Coding regions of known genes were excluded. With this setup of SNPs, we have calculated the average exclusion power in paternity testing to be 86.5%. The array was vali...
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Minisatellite variant repeat (MVR) mapping using polymerase chain reaction (PCR) was applied to a practical case of paternity testing to evaluate the paternity probability. In order to obtain single allele mapping by allele-specific MVR-PCR, three flanking polymorphic sites for each of the MS31A and MS32 loci were investigated and all three individuals were typed as heterozygous for at least on...
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The principles of paternity exclusion and current systems of paternity testing are reviewed. Recent advances, especially the utilization of human leukocyte antigens (HLA), have greatly improved the likelihood of exclusion of the innocent accused male. Failure to exclude an alleged father through multiple test systems increases the suspicion that he is the biological father. This can be expresse...
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